Early brain activity changes in healthy adults, linked to Alzheimer’s proteins, predict cognitive decline.
In our new Nature Neuroscience study, we have discovered that early changes in brain activity respectively related to amyloid-beta and tau buildup can predict cognitive decline years before symptoms appear, offering hope for early detection of Alzheimer’s. The study also highlights the potential of short MEG scans to identify those at risk long before memory loss sets in.
The Neurochemical Landscape of Alzheimer’s Disease.
Our latest study investigates how changes in brain activity align with the distribution of neurotransmitters in Alzheimer’s disease. Published in open access by Alzheimer’s & Dementia, our research found that these changes are closely linked to areas rich in cholinergic receptors, which are also where amyloid-β plaques tend to accumulate. This alignment is connected to the severity of Alzheimer’s cognitive symptoms, offering new insights into potential diagnostic markers and therapeutic targets.
The brain-fingerprint of Parkinson’s disease.
Our lab publishes in the journal eBiomedicine, which is part of The Lancet group, a new study that reveals distinct patterns of brain activity that differentiate individuals with Parkinson’s disease.
Brain Imaging Data Structure (BIDS): a retrospective.
We are both happy and proud to have played a little part (MEG-BIDS) in this collective effort to promote collaboration and structured data sharing in neuroimaging research. New retrospective paper just published by MIT Press' Imaging Neuroscience.
Brain Changes in Parkinson's Disease: from Chemistry to Anatomy.
We publish in Annals of Neurology a new study that advances the fundamental understanding of Parkinson's disease beyond its motor symptoms. Our findings underscore the importance of considering the neurochemical organization of the cortex in the disease and its implications for treatment and management. As we continue to explore these complex relationships, we move closer to more targeted and effective therapies for PD patients.
Hard to focus!
We publish in Cerebral Cortex a new study in collaboration with Jérôme Sackur at Ecole Normale Supérieure (Paris) that explored how different types of attention interact in the brain.
We recorded brainwaves with EEG to study how involuntary attention (like a sudden sound grabbing your attention) can interrupt voluntary attention (like focusing on a task). Our findings shed light on the complex ways our brain juggles different attention processes, offering new insights into how our mind manages focus and distractions.
Brain and pain: a two-way street.
We publish in the journal PAIN reports a new study that advances the understanding of the complex and multifaceted brain signals that convey the perception of pain.
The Dual Nature of Brain Changes in Parkinson’s Disease.
When slow is not necessarily a low. We show in a new study just published in Progress in Neurobiology how a slowing of brain activity may be protective of brain functions in the natural history of Parkinson’s Disease.
Speech impairments in Parkinson’s disease: the brain perspective.
Our new study published today in open access by npj Parkinson’s Disease clarifies the neurophysiological manifestations of speech impairments in Parkinson’s disease using advanced functional brain imaging.
Two eyes, one vision, except when not.
We took part in another fruitful collaborative study led by vision neuroscience specialist Prof Janine Mendola, which was just published in the European Journal of Neuroscience in open access.
Spinal cord stimulation against chronic pain: why conflicting outcomes?
In a new study published today in the journal Neuromodulation, we report the brain responses to spinal cord stimulation, a treatment for individuals afflicted by severe chronic pain. We found that these brain responses are remarkably variable across patients, which may account for the fact that the benefits of spinal cord stimulation on chronic pain vary greatly between individuals.
The neurochemistry of the structural and functional organization of the human brain.
In another winning collaboration with Prof Bratislav Misic, we show how markers of brain activity and structure relate to the topography of neurotransmitter systems across the cortex. This new study is published by Nature Neuroscience.
New collaborative study clarifies the origins of epileptic seizures.
Our new collaborative study, published in Epileptic Disorders clarifies how seizures propagate across the brain in certain types of general epilepsy.
A new tool for the interpretation of brain structures and functions.
We were fortunate to work with Prof Bratislav Misic and collaborators to deliver neuromaps, a toolbox for accessing, transforming and analyzing structural and functional brain annotations in a common framework.
The details are reported in a new article published in Nature Methods.
Time-tracking the spectrum of complex neural dynamics.
We publish today in eLife, a new method that decomposes brain activity into oscillatory and background signal elements that vary at the natural time scale of the brain and behavior. Check it out with the companion open-source code or with Brainstorm!
Deep down, we’re aging.
We publish today in Cerebral Cortex a study that advances our understanding of the effects of biological aging on the neurophysiology of deeper brain structures that are crucial to cognitive functions.
New paper details the association between haemodynamic & electrophysiological brain signals
A new study conducted by Golia Shafiei, in the team of Bratislav Misic at The Neuro/McGill, in collaboration with our lab was just published in PLoS Biology. The study advances our comprehension of how functional MRI signals relate to electrophysiological fluctuations detected with MEG in brain networks.
Go with the flow: how the brain motor system helps us process sound streams
We constantly process sounds that come in streams, embedded in a certain context — think music and speech for instance. How salient sounds standing out from a flow of auditory information are detected and processed by brain circuits was the purpose of our new study, just published in the Journal of Neuroscience.
A novel experimental paradigm to study conscious perception
A new journal article published today in Consciousness and Cognition by Max Levinson and Sylvain Baillet introduces an experimental paradigm that disentangles between the conscious processes and the sensory brain signals of perception.
Boosting (auditory) memory with (visual) stimulations
Our new study shows that stimulating one of our senses enhances our capacity to memorize inputs to our other senses.
The results, obtained in collaboration with the Zatorre lab, also at McGill’s Montreal Neurological Institute, are published today in open access in the journal Science Advances.