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Early brain activity changes in healthy adults, linked to Alzheimer’s proteins, predict cognitive decline.
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Early brain activity changes in healthy adults, linked to Alzheimer’s proteins, predict cognitive decline.

In our new Nature Neuroscience study, we have discovered that early changes in brain activity respectively related to amyloid-beta and tau buildup can predict cognitive decline years before symptoms appear, offering hope for early detection of Alzheimer’s. The study also highlights the potential of short MEG scans to identify those at risk long before memory loss sets in.

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The Neurochemical Landscape of Alzheimer’s Disease.
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The Neurochemical Landscape of Alzheimer’s Disease.

Our latest study investigates how changes in brain activity align with the distribution of neurotransmitters in Alzheimer’s disease. Published in open access by Alzheimer’s & Dementia, our research found that these changes are closely linked to areas rich in cholinergic receptors, which are also where amyloid-β plaques tend to accumulate. This alignment is connected to the severity of Alzheimer’s cognitive symptoms, offering new insights into potential diagnostic markers and therapeutic targets.

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Brain Changes in Parkinson's Disease: from Chemistry to Anatomy.
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Brain Changes in Parkinson's Disease: from Chemistry to Anatomy.

We publish in Annals of Neurology a new study that advances the fundamental understanding of Parkinson's disease beyond its motor symptoms. Our findings underscore the importance of considering the neurochemical organization of the cortex in the disease and its implications for treatment and management. As we continue to explore these complex relationships, we move closer to more targeted and effective therapies for PD patients.

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Hard to focus!
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Hard to focus!

We publish in Cerebral Cortex a new study in collaboration with Jérôme Sackur at Ecole Normale Supérieure (Paris) that explored how different types of attention interact in the brain.

We recorded brainwaves with EEG to study how involuntary attention (like a sudden sound grabbing your attention) can interrupt voluntary attention (like focusing on a task). Our findings shed light on the complex ways our brain juggles different attention processes, offering new insights into how our mind manages focus and distractions.

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Spinal cord stimulation against chronic pain: why conflicting outcomes?
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Spinal cord stimulation against chronic pain: why conflicting outcomes?

In a new study published today in the journal Neuromodulation, we report the brain responses to spinal cord stimulation, a treatment for individuals afflicted by severe chronic pain. We found that these brain responses are remarkably variable across patients, which may account for the fact that the benefits of spinal cord stimulation on chronic pain vary greatly between individuals.

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Boosting (auditory) memory with (visual) stimulations
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Boosting (auditory) memory with (visual) stimulations

Our new study shows that stimulating one of our senses enhances our capacity to memorize inputs to our other senses.

The results, obtained in collaboration with the Zatorre lab, also at McGill’s Montreal Neurological Institute, are published today in open access in the journal Science Advances.

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